Genetic and Familial Breast Cancer

Although the vast majority of breast cancer cases are associated with environmental and lifestyle factors, genetic predisposition plays an important role in some patients. In particular, breast cancer occurring at a young age in family members, the presence of breast or ovarian cancer in more than one person in the same family, or a history of male breast cancer should be carefully evaluated in terms of hereditary breast cancer.

Today, thanks to genetic testing, some gene mutations that increase the risk of breast cancer can be detected at an early stage. In particular, changes in the BRCA1 and BRCA2 genes may significantly increase a person’s lifetime risk of developing breast and ovarian cancer. Therefore, regular follow-up and preventive approaches are of great importance for individuals in the high-risk group.

As Prof. Dr. Atakan Sezer, we evaluate our patients with genetic risk not only in terms of their current disease, but also in terms of risks that may arise in the future. When necessary, genetic counseling processes are planned, personalized screening programs are created, and patients are followed with a multidisciplinary approach.

“Genetic predisposition is not destiny; with proper follow-up and early intervention, risks can be managed to a great extent.”

The prominent approaches in the management of genetic and familial breast cancer are as follows:

Risk Assessment: Determining hereditary cancer risk by thoroughly examining the family history.

Genetic Tests: Investigating BRCA and other related gene mutations in appropriate patients.

Personalized Screening Programs: Planning imaging methods such as mammography, breast ultrasonography, and breast MRI according to the level of risk.

Preventive Approaches: Evaluating lifestyle modifications, medical treatments, or preventive surgical options when necessary in high-risk individuals.

If you have a family history of breast or ovarian cancer, it is of great importance to learn your risk and take the necessary precautions in time. In our clinic in Edirne, we continue to support individuals with genetic risk in their diagnosis, follow-up, and treatment processes with current approaches developed in the light of scientific data.